Flagship

Flagship Pioneering is seeking a Lead Cloud Security/AppSec Engineer in Cambridge, MA to build their cloud security and application security engineering practice. The role involves defining cloud posture management, SSDLC security, and AI-augmented workflows in partnership with Infrastructure teams. Candidates require 5+ years of experience in cloud security, AWS, and identity platforms.

Flagship Pioneering is seeking a Principal Scientist specializing in Machine Learning and Genomics within their Pioneering Intelligence division. The role involves leading AI/ML projects across early-stage ventures, overseeing method development, and managing cross-functional teams. Candidates should have a PhD or Master's with significant experience in computational sciences and AI/ML frameworks.

Flagship Pioneering is seeking a Principal Scientist to lead AI/ML projects across early-stage ventures. The role involves defining pragmatic AI strategies, overseeing method development, and managing cross-functional contributors within the Pioneering Intelligence division. Candidates should have a PhD or Master's with significant experience in computational sciences or machine learning.

We are seeking a Scientist to join a dynamic team applying computational and data-driven approaches to design novel antigens and evaluate vaccine responses. At Apriori Bio, we have built our biology-enabled AI/ML platform Octavia™ to map viral fitness landscapes, predict immune escape trajectories, and design vaccines to elicit an optimal protective response to future challenges. The successful candidate will contribute to the development and application of computational methods—including structural modeling, machine learning, and statistical inference— that build on Octavia™ insights to support the company’s vaccine design efforts.

Vesalius Therapeutics is seeking a Senior Scientist in Computational Biology with 5+ years of experience in high-dimensional data analysis. The role involves developing statistical methods for iPSC-based phenotyping platforms, mentoring junior scientists, and collaborating across teams to redefine common diseases using genetic and phenotypic data. Candidates must hold a PhD in Statistics, Biostatistics, Computer Science, or Mathematics with strong programming skills in Python or R.

Flagship Labs 109, Inc. is seeking innovative professionals to join its interdisciplinary team developing AI solutions integrating physics and hardware for molecular biology. The role involves building scalable platforms and managing datasets within a mission-driven biotech environment. Open Call positions include talent needs in AI, software engineering, automation, physics, and hardware engineering.

Extuitive, Inc., a Flagship Pioneering-backed startup, is seeking a Principal Backend Developer in Cambridge, MA. The role involves architecting scalable backend systems, leading engineering teams, and driving AI product innovation. Candidates must have 8+ years of experience and expertise in distributed systems.

Flagship Pioneering is seeking a Principal Product Manager for their Pioneering Intelligence initiative in Cambridge, MA. The role involves owning product vision and strategy for Agentic AI within the life sciences sector. Candidates need 7+ years of experience in biotech or life sciences product management.

Flagship Pioneering is seeking a Principal Scientist, Machine Learning, Biomolecules in Cambridge, MA. The role involves leading AI/ML projects across early-stage ventures, overseeing method development, and managing cross-functional teams. Candidates need a PhD or Master's with 5+ years of experience in computational sciences or AI/ML.

Flagship Pioneering is seeking a (Senior) Director, Data Platform Product Manager to lead product strategy and execution for their shared data platform. The role involves working with AI/ML engineers and scientists to build secure, well-governed data access across the portfolio. Candidates need 7+ years of product management experience with a focus on data platforms and infrastructure.

Flagship Pioneering is seeking a Senior Platform Engineer to strengthen and scale AWS-based infrastructure at Montai Therapeutics. The role involves designing cloud systems, implementing CI/CD pipelines, and ensuring platform reliability using Python and infrastructure-as-code. Candidates should have 6+ years of experience in Platform, DevOps, or Backend Infrastructure Engineering.

Flagship Labs 119 Inc., backed by Flagship Pioneering, is hiring a Senior / Principal Neuromorphic Systems Architect in Cambridge, MA. The role focuses on designing next-generation computational architectures at the intersection of neuroscience and hardware engineering. Candidates require a PhD or equivalent experience in fields like Electrical Engineering or Computational Neuroscience.

Flagship Pioneering is seeking a (Senior) Scientist, Machine Learning for their new venture Flagship Labs 120. This zero-to-one role involves building ML models for complex physical systems and defining technical foundations. Candidates should have strong experience in deep learning, representation learning, and working with real-world data.

Flagship Pioneering is seeking a Senior UX Designer to focus on Agentic AI products within the life sciences sector. The role involves designing intuitive user experiences for AI-powered tools and collaborating with multidisciplinary teams to solve impactful challenges. Candidates require 5-6 years of experience in scientific product design.

Flagship Pioneering is seeking a Senior Vice President for AI & Digital Platform to lead their Pioneering Intelligence team. The role involves defining AI strategy, building digital infrastructure, and managing technology teams within a life sciences ecosystem. This senior leadership position requires extensive experience in AI, data platforms, and organizational leadership.

Flagship Pioneering, Inc. is seeking a Vice President of Data Platform to lead the strategy and development of AI-native data technologies within Pioneering Intelligence. This role involves partnering with scientific and technical colleagues to enable new AI capabilities while maintaining strong controls and compliance across the portfolio.

ProFound Therapeutics, a Flagship Pioneering company, is seeking a (Senior) Data Engineer to build the data foundation for its drug discovery platform. The role involves architecting systems integrating biological data, building production pipelines, and managing cloud infrastructure on AWS.